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Joint Injections for Horses | PetMD

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Joint injections are a common topic for horse owners—especially if your horse is aging, in competition, or both. Whether joint injections are right for your horse is a decision that deserves careful consideration. 

Key Takeaways

  • Joint injections are a therapy used to reduce inflammation and pain within a horse’s joints.
  • They are performed to treat lameness and improve performance.
  • Injections must be administered by a veterinarian.
  • After the procedure, your horse will need a follow-up period of rest—sometimes with NSAIDs—followed by a gradual return to work.

Why Does a Horse Need Joint Injections?

A joint is anywhere on the horse’s body where two bones come together. Surrounding that space is a structure called the joint capsule, which contains joint fluid (synovial fluid). Synovial fluid is composed of large molecules (hyaluronan) and other proteins.  The ends of the bones are also covered in cartilage. 

Both the cartilage and joint fluid provide a cushion and prevent the two bones from rubbing against each other. When the cartilage breaks down or the joint fluid thins, bone can slide against bone, causing pain and inflammation, as well as changes in the bone structure itself.  

These changes often result in lameness and reduce range of motion in the horse’s stride.   

Any time a horse experiences inflammation of a joint, injections can help relieve pain and inflammation and increase range of motion.  

Common conditions that may benefit from joint injection use include:  

Joint injections provide pain relief by reducing inflammation. Corticosteroids block the inflammation receptor pathways, and reducing inflammation also helps protect cartilage from further damage.  

Types of Joint Injections for Horses

Steroids  

Corticosteroids are synthetic steroid drugs that reduce pain and inflammation. They are generally cheap and readily available, but overuse has been shown to cause cartilage damage in horses over time.  

Steroids should also be used with caution or not at all in horses who are metabolic or prone to laminitis.  

Hydrogels  

Hydrogels, such as Arthramid and Noltrex, provide pain relief by forming a gel buffer in the joint that acts as a fluid cushion between the bones. 

Hyaluronic Acid  

Large molecules like hyaluronic acid help to improve the quality of the joint fluid by helping to make the fluid more viscous. As a horse ages, the joint fluid can become thinner and less viscous, providing less cushion in the joint.  

Orthobiologics  

Platelet rich plasma (PRP) and interleukin-1 receptor antagonist protein (IRAP) are derived from the horse’s own blood and prepared in a lab before being injected into the joint. These treatments help reduce inflammation and slow degenerative changes.  

Oral anti-inflammatories, like phenylbutazone, Banamine, or Equioxx, can be given alone or alongside Adequan. However, long-term NSAID use carries potential side effects, so talk to your vet before starting these medications. 

Joint supplements containing hyaluronic acid (HA) or glucosamine can be added to your horse’s feed, but these are better for maintenance, as you won’t see as dramatic an effect as you would with injectables. 

Horse Joint Injections FAQs

What is the best joint injection for horses?

The cheapest and most commonly used intra-articular injection in horses is corticosteroids combined with hyaluronic acid. It does not, however, mean that it is the best option for every horse. Discuss with your veterinarian which type of injections are best for your horse.

How long do joint injections last in horses?

How much do joint injections cost?

The cost of joint injections is $200–$1,000 per visit, depending on the product being injected and number of joints being injected.

What do vets inject into horse joints?

Veterinarians can inject a combination of corticosteroids, hyaluronic acid, autologous blood products (PRP, IRAP), and hydrogels into joints. 

When do you see the maximum benefit from joint injections?

For corticosteroids, horses typically experience the maximum benefit around seven days after injection. Hydrogels take longer, with peak effects often seen after 30 days or more.


WRITTEN BY

Sandy Tasse, DVM

Veterinarian

Dr. Tasse grew up in New Jersey riding horses. She attended undergrad in Pennsylvania, and then went to veterinary school at Oklahoma State…


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